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Irene Hernández-Lozano Selected Research

Member 1 Subfamily B ATP Binding Cassette Transporter

1/2022PET imaging to assess the impact of P-glycoprotein on pulmonary drug delivery in rats.
1/2022Impact of P-gp and BCRP on pulmonary drug disposition assessed by PET imaging in rats.
8/2021Assessing the Functional Redundancy between P-gp and BCRP in Controlling the Brain Distribution and Biliary Excretion of Dual Substrates with PET Imaging in Mice.
1/2021Complete inhibition of ABCB1 and ABCG2 at the blood-brain barrier by co-infusion of erlotinib and tariquidar to improve brain delivery of the model ABCB1/ABCG2 substrate [11C]erlotinib.

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Irene Hernández-Lozano Research Topics

Disease

4Breast Neoplasms (Breast Cancer)
01/2022 - 01/2021
1Chronic Obstructive Pulmonary Disease (COPD)
05/2023
1Cystic Fibrosis (Mucoviscidosis)
05/2023
1Amyloidosis
06/2022
1Inflammation (Inflammations)
03/2022
1Endotoxemia
03/2022
1Lung Diseases (Lung Disease)
01/2022
1Liver Diseases (Liver Disease)
05/2020

Drug/Important Bio-Agent (IBA)

4Member 1 Subfamily B ATP Binding Cassette TransporterIBA
01/2022 - 01/2021
4Proteins (Proteins, Gene)FDA Link
01/2022 - 01/2021
2multidrug resistance-associated protein 1IBA
05/2023 - 06/2022
2Adenosine Triphosphate (ATP)IBA
01/2022 - 08/2021
2ATP-Binding Cassette Transporters (ABC Transporters)IBA
01/2022 - 08/2021
1AntiemeticsIBA
06/2022
1Thiethylperazine (Thiethylperazine Malate)FDA Link
06/2022
1Organic Anion TransportersIBA
03/2022
1AnionsIBA
03/2022
1Bile Acids and Salts (Bile Acids)IBA
03/2022
1Peptides (Polypeptides)IBA
03/2022
1Rifampin (Rifampicin)FDA LinkGeneric
03/2022
1Multidrug Resistance-Associated ProteinsIBA
08/2021
1Ciprofloxacin (Cipro)FDA LinkGeneric
08/2021
1technetium Tc 99m mebrofeninFDA LinkGeneric
05/2020